Why is Tadora 20 Mg classified as a phosphodiesterase type 5 (PDE5) inhibitor?

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stephenbarkin

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Tadora 20 mg is classified as a phosphodiesterase type 5 (PDE5) inhibitor because it contains the active ingredient tadalafil, which acts specifically on the PDE5 enzyme. PDE5 is an enzyme found in various tissues in the body, but it is most concentrated in the smooth muscle cells of the penis.

Here's how Tadora 20 mg and other PDE5 inhibitors work:
Normal Erection Process: In men, sexual arousal triggers the release of nitric oxide (NO) in the corpus cavernosum, a sponge-like tissue in the penis. Nitric oxide helps relax the smooth muscle cells within the blood vessels of the penis, leading to increased blood flow. This increased blood flow fills the penile chambers and results in an erection.
Role of PDE5: To end an erection and return the penis to its flaccid state after sexual activity, the body releases another enzyme called phosphodiesterase type 5 (PDE5). PDE5 breaks down cyclic guanosine monophosphate (cGMP), a chemical responsible for relaxing the smooth muscle cells in the penis. As cGMP levels decrease, the smooth muscle cells contract, reducing blood flow, and causing the erection to subside.
PDE5 Inhibition by Tadalafil: Tadalafil, the active ingredient in Tadora 20 mg, works by inhibiting PDE5. By blocking PDE5, tadalafil allows cGMP levels to remain elevated for a longer time, promoting the relaxation of penile smooth muscle cells and facilitating increased blood flow to the penis. This results in improved erectile function and the ability to achieve and maintain an erection when sexually aroused.