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Malegra Oral Jelly can be taken either before or after eating. When taking Malegra Oral Jelly, you should follow the directions given to you by your doctor. Take Malegra Oral Jelly 30 to 60 minutes prior to sexual activity with a glass of regular water. Always follow the directions on the prescription or label. This medication will only help you get an erection if you are already awake. It works, but you have to take it at least 30 minutes before having a sexual encounter. PDE5 inhibitors are a class of medications that include Malegra Oral Jelly The main ingredient is 100 milligrams of Sildenafil Citrate.